The museum founded in 1878 administers several permanent expositions in Znojmo and surroundings. Located at the Znojmo castle with the valuable rotunda of the Virgin Mary and St. Kateřina is a historic exposition and lapidary. In the Minorites' monastery there is the seat of the natural science, archaeological and numismatic collections together with a unique collection of Oriental weapons, the museum also administers the castle Cornštejn and the Memorial of P. Diviš in Přímětice.